Detail
| LncRNA Name | RP11-68I18.10 |
| Synonyms | RP11-68I18.10 |
| Region | GRCh38_1:151130075-151131610 Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✔ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | childhood acute lymphoblastic leukemia |
| ICD-0-3 | M9835/3 |
| Methods | qPCR etc. |
| Sample | cell lines (Reh, NALM-6) |
| Expression Pattern | up-regulated |
| Function Description | We validated that five such lncRNA transcripts overexpressed in pre-B cALL samples (RP11-137H2.4, RP11-68I18.10, AC156455.1, KB-208E9.1, and CTA-331P3.1) were also overexpressed in the Reh and NALM-6 pre-B cALL cell lines that had significant impacts on cancer hallmark traits such as cell proliferation, migration, apoptosis, and treatment response. |
| Pubmed ID | 27980230 |
| Year | 2017 |
| Title | A childhood acute lymphoblastic leukemia-specific lncRNA implicated in prednisolone resistance, cell proliferation, and migration. |
| External Links |
| Links for RP11-68I18.10 | GenBank HGNC lncrnadb Noncode |
| Links for childhood acute lymphoblastic leukemia | Omim Cosmic |
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