Detail
| LncRNA Name | RP11-766N7.4 |
| Synonyms | LINC02231 |
| Region | GRCh38_12:64920845-64982524 Sequence |
| Ensembl | ENSG00000248995 |
| RefSeq | NR_146276 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | esophageal squamous cell cancer |
| ICD-0-3 | |
| Methods | qPCR, RNAi, Western blot, Flow cytometry assay, Cell proliferation assay etc. |
| Sample | ESCC tissues, cell lines (TE-13, TE-1, EC-1 and Eca-109) |
| Expression Pattern | down-regulated |
| Function Description | RP11-766N7.4 was downregulated in ESCC tissues and cell lines and correlated with lymph node metastasis, tumor stage and survival rate. In addition, long noncoding RNA RP11-766N7.4 knockdown promoted cellular migration and invasion via inducing EMT process, and overexpression of long noncoding RNA RP11-766N7.4 inhibited cellular migration and invasion by suppressing EMT process. |
| Pubmed ID | 28157654 |
| Year | 2017 |
| Title | Long noncoding RNA RP11-766N7.4 functions as a tumor suppressor by regulating epithelial-mesenchymal transition in esophageal squamous cell carcinoma. |
| External Links |
| Links for RP11-766N7.4 | GenBank HGNC lncrnadb Noncode |
| Links for esophageal squamous cell cancer | Omim Cosmic |
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