Detail
| LncRNA Name | RP11-838N2.4 |
| Synonyms | NA |
| Region | GRCh38_18:3466250-3478978 Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✔ |
| Drug-resisitant | ✔ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 M8046/3 |
| Methods | Microarray, qPCR, Western blot etc. |
| Sample | non small cell lung cancer tissues, serum, cell lines (HCC827 and HCC4006) |
| Expression Pattern | up-regulated |
| Function Description | In addition, the serum expression levels of exosomal lncRNA RP11-838N2.4 were upregulated in patients exhibiting resistance to erlotinib treatment. On the whole, exosomal lncRNA RP11-838N2.4 may serve as a therapeutic target for patients with NSCLC. |
| Pubmed ID | 29845246 |
| Year | 2018 |
| Title | Exosome-mediated transfer of lncRNA RP11-838N2.4 promotes erlotinib resistance in non-small cell lung cancer |
| External Links |
| Links for RP11-838N2.4 | GenBank HGNC lncrnadb Noncode |
| Links for non small cell lung cancer | Omim Cosmic |
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