Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name RP1-4514.2
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name prostate cancer
   ICD-0-3 C61.9  
   Methods microarray, qPCR etc.
   Sample prostate cancer tissues, cell lines (LNCaP)
   Expression Pattern down-regulated
   Function Description

Five lncRNAs, RP1-4514.2, SUZ12P1, SNHG5, LINC01138, and SNHG1, were down-regulated under DHT treatment. Five lncRNAs, KLKP1, LINC00969, LINC-PINT, TUG1 and MIR17HG, were up-regulated under DHT treatment. Notably, RP1-4514.2 and LINC01138 were induced and KLKP1 was reduced over 2 fold after AR silenced, suggesting the involvement of AR in androgen-mediated regulation of these lncRNAs expressions.

   Pubmed ID 27556357
   Year 2016
   Title Identification of androgen-responsive lncRNAs as diagnostic and prognostic markers for prostate cancer.
   External Links
   Links for  RP1-4514.2 GenBank       HGNC       lncrnadb       Noncode
   Links for  prostate cancer Omim       Cosmic

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