Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name RP5-833A20.1
   Synonyms NFIA-AS1
   Region GRCh38_1:61248945-61253510    Sequence
   Ensembl ENSG00000237853
   RefSeq NR_104180
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioma
   ICD-0-3  M9380/3
   Methods qPCR, Cell transfection, Western blot, Cell proliferation assay etc.
   Sample glioma tissues, cell line (U251)
   Expression Pattern down-regulated
   Function Description

The expression of RP5-833A20.1 was downregulated, whereas the expression of NFIA was upregulated in glioma tissues, compared with corresponding adjacent nontumor tissues from 20 patients with glioma. The overexpression of RP5-833A20.1 inhibited proliferation and cell cycle progression, and induced apoptosis in the U251 cells.

   Pubmed ID 27779670
   Year 2016
   Title Long non-coding RNA RP5-833A20.1 inhibits proliferation, metastasis and cell cycle progression by suppressing the expression of NFIA in U251 cells.
   External Links
   Links for  RP5-833A20.1 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioma Omim       Cosmic

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