Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name RPL34-AS1
   Synonyms FLJ37673, RP11-462C24.1
   Region GRCh38_4:108538190-108620460    Sequence
   Ensembl ENSG00000234492
   RefSeq NR_026968
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods microarray, qPCR etc.
   Sample CRC tissues
   Expression Pattern down-regulated
   Function Description

We found that RP11-462C24.1 expression level was lower in cancer tissues compared with adjacent normal samples. Furthermore, its expression level was lower in CRC patients with metastasis than those without metastasis. That is, RP11-462C24.1 expression level decreased as the malignant degree of CRC increased. In addition, low expression of RP11-462C24.1 significantly correlated with more distant metastasis.

   Pubmed ID 24908062
   Year 2014
   Title Low expression of novel lncRNA RP11-462C24.1 suggests a biomarker of poor prognosis in colorectal cancer.
   External Links
   Links for  RPL34-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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