Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name RPPH1
   Synonyms H1RNA, RPPH1-1
   Region GRCh38_14:20343048-20343685    Sequence
   Ensembl ENSG00000277209
   RefSeq NR_002312
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample cell lines (MCF-7, MDA-MB-231)
   Expression Pattern up-regulated
   Function Description

RPPH1 functions as a tumour promoter and plays an important role in advancing tumorigenesis by targeting miR-122 and may serve as a novel and potential therapeutic, diagnostic or prognostic target in breast cancer.

   Pubmed ID 29200969
   Year 2017
   Title Inhibition of breast cancer cell proliferation and tumorigenesis by long non-coding RNA RPPH1 down-regulation of miR-122 expression.
   External Links
   Links for  RPPH1 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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