Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SAMMSON
   Synonyms LINC01212
   Region GRCh38_3: 69999550-70518064    Sequence
   Ensembl ENSG00000240405
   RefSeq NR_110000
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name melanoma
   ICD-0-3  M8720/3
   Methods qPCR, RIP etc.
   Sample cell lines (Mel501, SK-MEL-28), melanoma tissues
   Expression Pattern up-regulated
   Function Description

Our results indicate that silencing of the lineage addiction oncogene SAMMSON disrupts vital mitochondrial functions in a cancer-cell-specific manner; this silencing is therefore expected to deliver highly effective and tissue-restricted antimelanoma therapeutic responses.

   Pubmed ID 27008969
   Year 2016
   Title Melanoma addiction to the long non-coding RNA SAMMSON
   External Links
   Links for  SAMMSON GenBank       HGNC       lncrnadb       Noncode
   Links for  melanoma Omim       Cosmic

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