Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SFTA1P
   Synonyms SFTA1P, SFTPF
   Region GRCh38_10:10784437-10794980    Sequence
   Ensembl ENSG00000225383
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung adenocarcinoma
   ICD-0-3 C34  M8140/3
   Methods qPCR, Cell transfection, Cell migration and invasion assay etc.
   Sample LAD tissues, cell lines (A549, H1975, SPC-A1, PC9, H1299, H1650, and SK-MES-1)
   Expression Pattern down-regulated
   Function Description

SFTA1P expression was down-regulated in all LUAD cell lines compared with HBE. In addition, gain-of-function studies including growth curves, migration, invasion assays, and in vivo studies were performed to verify the tumor suppressor role of SFTA1P in non-small cell lung cancer.

   Pubmed ID 28231733
   Year 2017
   Title The pseudogene-derived long noncoding RNA SFTA1P is down-regulated and suppresses cell migration and invasion in lung adenocarcinoma.
   External Links
   Links for  SFTA1P GenBank       HGNC       lncrnadb       Noncode
   Links for  lung adenocarcinoma Omim       Cosmic

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