Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name snaR
   Synonyms SNAR-A1, SNAR-A53113498
   Region GRCh19:47918429-47918550    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR, RNAi, MTT assay etc.
   Sample cell lines (MDA-MB-231, MCF-7, SKBR3, T47D, BT474, BT20)
   Expression Pattern up-regulated
   Function Description

LncRNA snaR was found to be up-regulated in breast cancer cells, and the cancer progression of MDA-MB-231 cells was significantly suppressed by down-regulation of snaR. Therefore, snaR knockdown has potential as a treatment modality for triple-negative breast cancer.

   Pubmed ID 27919948
   Year 2016
   Title Long Noncoding RNA snaR Regulates Proliferation, Migration and Invasion of Triple-negative Breast Cancer Cells.
   External Links
   Links for  snaR GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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