Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SNHG1
   Synonyms SNHG1, LINC00057, NCRNA00057, U22HG, UHG, lncRNA16
   Region GRCh38_11:62851988-62855914    Sequence
   Ensembl ENSG00000255717
   RefSeq NR_003098
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name neuroblastoma
   ICD-0-3  M9500/3
   Methods qPCR
   Sample cell lines (SK-N-DZ, SK-N-SH, SK-N-BE(2)-C)
   Expression Pattern up-regulated
   Function Description

In conclusion, our study unveils that SNHG1 is up-regulated by MYCN amplification and could be a potential prognostic biomarker for high-risk NB intervention. Kaplan-Meier analysis shows that higher expression of SNHG1 is significantly associated with poor patient survival.

   Pubmed ID 27517149
   Year 2016
   Title Co-expression analysis identifies long noncoding RNA SNHG1 as a novel predictor for event-free survival in neuroblastoma
   External Links
   Links for  SNHG1 GenBank       HGNC       lncrnadb       Noncode
   Links for  neuroblastoma Omim       Cosmic

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