Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name BC200
   Synonyms BCYRN1, BC200, BC200a, LINC00004, NCRNA00004
   Region GRCh38_2:47335315-47335514    Sequence
   Ensembl ENSG00000236824
   RefSeq NR_001568
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods microarray, qPCR, Cell proliferation assay etc.
   Sample cell lines (PC9, H1975, H1299 and A549)
   Expression Pattern up-regulated
   Function Description

Overexpression of H19 and BC200 were observed in gefitinib-resistant lung cancer cell lines (PC9/R, A549, H1299 and H1975). However, in the gefitinib-sensitive cell line (PC9), MALAT1 and HOTAIR were downregulated.

   Pubmed ID 25482516
   Year 2015
   Title Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer.
   External Links
   Links for  BC200 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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