Detail
| LncRNA Name | SNHG12 |
| Synonyms | SNHG12, ASLNC04080, C1orf79, LINC00100, NCRNA00100, PNAS-123 |
| Region | GRCh38_1:28578538-28582983 Sequence |
| Ensembl | ENSG00000197989 |
| RefSeq | NR_024127 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | endometrial cancer |
| ICD-0-3 | M8380/3 |
| Methods | microarray, qPCR etc. |
| Sample | endometrial carcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | ASLNC04080 was the most significantly upregulated lncRNA in microarray data, highly expressed in 22 out of 24 endometrial carcinoma tissues and HEC-1-B cell line. Moreover, the ASLNC04080 lncRNA expression was correlated with 19 coding genes, and may contribute to endometrial carcinoma genesis and progression by co-regulating with coding gene. Expression inhibition of lncRNA ASLNC04080 in HEC-1-B cells caused repression of cell proliferation, increased cell apoptosis, and G1 phase arrest. |
| Pubmed ID | 25695231 |
| Year | 2015 |
| Title | Microarray expression profile of lncRNAs and the upregulated ASLNC04080 lncRNA in human endometrial carcinoma. |
| External Links |
| Links for SNHG12 | GenBank HGNC lncrnadb Noncode |
| Links for endometrial cancer | Omim Cosmic |
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