NHG12 was found to be abnormally elevated in human cervical cancer tissues compared with paired adjacent normal tissues.high SNHG12 expression in tumor tissues was significantly correlated with vascular involvement,lymph node metastasis,advanced FIGO stage and poor prognosis.the knockdown of SNHG12 was found to inhibit proliferation,migration and invasion of cervical cancer cells in vitro, and silencing SNHG12 was shown to suppress tumor growth in a nude mouse model. SNHG12 functioned as an endogenous sponge for miR-424-5p, thereby downregulating the expression of miR-424-5p in cervical cancer.the inhibition of miR-424-5p in SNHG12-depleted cells partially reversed the effects on cervical cancer cell apoptosis, adhesion and invasion.