Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name SNHG12
   Synonyms SNHG12, ASLNC04080, C1orf79, LINC00100, NCRNA00100, PNAS-123
   Region GRCh38_1:28578538-28582983    Sequence
   Ensembl ENSG00000197989
   RefSeq NR_024127
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name papillary thyroid cancer
   ICD-0-3  M8260/3
   Methods qPCR, Western blot, in vitro knockdown etc.
   Sample cell lines (K1, BCPAP, TPC-1, Nthy-ori3-1), PTC tissue
   Expression Pattern up-regulated
   Function Description

The SNHG12 expression is relatively high in PTC tissues and cells. In-vivo/in-vitro experiments prove that SNHG12 can promote the proliferation and metastasis of PTC cells through influencing the Wnt/B-catenin signaling pathway.

   Pubmed ID 29630517
   Year 2018
   Title LncRNA SNHG12 promotes the proliferation and metastasis of papillary thyroid carcinoma cells through regulating wnt/B-catenin signaling pathway.
   External Links
   Links for  SNHG12 GenBank       HGNC       lncrnadb       Noncode
   Links for  papillary thyroid cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.