Detail
| LncRNA Name | SNHG12 |
| Synonyms | SNHG12, ASLNC04080, C1orf79, LINC00100, NCRNA00100, PNAS-123 |
| Region | GRCh38_1:28578538-28582983 Sequence |
| Ensembl | ENSG00000197989 |
| RefSeq | NR_024127 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioma |
| ICD-0-3 | C34 M8140/3 |
| Methods | qRT-PCR, RIP, RNA pull-down analysis, Western blot analysis |
| Sample | Primary tumor samples and matched adjacent non-carcinoma tissues, The normal human skin fibroblast HF cell line and the glioma cell lines, ( U87, LN229, U373 and U251 ) |
| Expression Pattern | up-regulated |
| Function Description | SNHG12 was significantly upregulated in glioma tissues and cell lines.The silencing of SNHG12 expression by RNA interference led to a reduced viability and mobility, and in an increased apoptosis of human glioma cells.SNHG12 was associated with and was stabilized by HuR. |
| Pubmed ID | 30015836 |
| Year | 2018 |
| Title | Long non-coding RNA SNHG12 promotes the proliferation and migration of glioma cells by binding to HuR. |
| External Links |
| Links for SNHG12 | GenBank HGNC lncrnadb Noncode |
| Links for glioma | Omim Cosmic |
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