Detail
| LncRNA Name | SNHG15 |
| Synonyms | SNHG15, C7orf40, Linc-Myo1g, MYO1GUT, FLJ38860, Linc-Myo1g |
| Region | GRCh38_7:44983023-44986961 Sequence |
| Ensembl | ENSG00000232956 |
| RefSeq | NR_003697 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc. |
| Sample | OS tissues, cell lines (143B, U2OS, HOS, MG63, and SaOS2) |
| Expression Pattern | up-regulated |
| Function Description | up-regulation of SNHG15 was inversely correlated with miR-141 expression in OS tissues.SNHG15 could directly interact with miR-141 and regulate its expression.SNHG15 contributes to proliferation, invasion, migration and autophagy in OS by negatively regulating miR-141,providing a new potential target and prognostic biomarker for the treatment of OS. |
| Pubmed ID | 28720111 |
| Year | 2017 |
| Title | LncRNA SNHG15 contributes to proliferation, invasion and autophagy in osteosarcoma cells by sponging miR-141. |
| External Links |
| Links for SNHG15 | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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