Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SNHG15
   Synonyms SNHG15, C7orf40, Linc-Myo1g, MYO1GUT, FLJ38860, Linc-Myo1g
   Region GRCh38_7:44983023-44986961    Sequence
   Ensembl ENSG00000232956
   RefSeq NR_003697
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR, Western blot, Luciferase reporter assay, RIP, etc.
   Sample human breast cancer cell lines. patient samples (fresh tumor tissues) or healthy donor blood.
   Expression Pattern down-regulated
   Function Description

Conclusion: Interference SNHG1 could inhibit the differentiation of Treg cells by promoting miR-448 expression and reducing IDO level, thereby impeding the immune escape of BC.

   Pubmed ID 29886172
   Year 2018
   Title LncRNA SNHG1 regulates the differentiation of Treg cells and affects the immune escape of breast cancer via regulating miR-448/IDO.
   External Links
   Links for  SNHG15 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

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