Detail
| LncRNA Name | SNHG16 |
| Synonyms | SNHG16, Nbla10727, Nbla12061, ncRAN |
| Region | GRCh38_17:76557766-76565348 Sequence |
| Ensembl | ENSG00000163597 |
| RefSeq | NR_038108 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR, Western blot, Luciferase reporter assay, in vitro knockdown, RIP |
| Sample | cervical cancer tissues, Cervical cancer cell lines (HeLa, CaSki, SiHa, and C33A) |
| Expression Pattern | up-regulated |
| Function Description | miR-216-5p could interact with SNHG16 and there existed a negative correlation between the expression levels of miR-216-5p and SNHG16 in cervical cancer specimens. SNHG16 directly targeted miR-216-5p by harboring the binding sites of microRNA in the SNHG16 sequence.Additionally, bioinformatics analysis provided an evidence that ZEB1 was a potential target of miR-216-5p. |
| Pubmed ID | 29126969 |
| Year | 2017 |
| Title | SNHG16/miR-216-5p/ZEB1 signal pathway contributes to the tumorigenesis of cervical cancer cells. |
| External Links |
| Links for SNHG16 | GenBank HGNC lncrnadb Noncode |
| Links for cervical cancer | Omim Cosmic |
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