Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SNHG5
   Synonyms SNHG5, C6orf160, LINC00044, U50HG, bA33E24.2, MGC16362, bA33E24.2, U50HG, NCRNA00044
   Region GRCh38_6:85660950-85678736    Sequence
   Ensembl ENSG00000203875
   RefSeq NR_003038
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods qPCR, Western blot, in vitro knockdown
   Sample BC tissues, Bladder cancer cell lines (SW780, UMUC3, 5637, T-24)
   Expression Pattern up-regulated
   Function Description

SNGH5 was found upregulated in BC tissues and cell lines and a high level of SNGH5 was correlated with a poor prognosis. Silencing SNHG5 inhibited the proliferation ability of BC cells and such a function was attributed to its influence on cells cycle and apoptosis.

   Pubmed ID 29434891
   Year 2017
   Title lncRNA SNHG5 is associated with poor prognosis of bladder cancer and promotes bladder cancer cell proliferation through targeting p27.
   External Links
   Links for  SNHG5 GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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