Detail
| LncRNA Name | SNHG5 |
| Synonyms | SNHG5, C6orf160, LINC00044, U50HG, bA33E24.2, MGC16362, bA33E24.2, U50HG, NCRNA00044 |
| Region | GRCh38_6:85660950-85678736 Sequence |
| Ensembl | ENSG00000203875 |
| RefSeq | NR_003038 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot, Luciferase reporter assay etc. |
| Sample | gastric cancer tissues, cell lines (SGC-7901 and MGC-803) |
| Expression Pattern | down-regulated |
| Function Description | SNHG5 contains a putative miR-32-binding site and that deletion of this site abolishes the responsiveness to miR-32. Suppression of SNHG5 expression by miR-32 was found to be Argonaute (Ago)2-dependent. Immunoprecipitation showed that SNHG5 could be pulled down from the Ago-2 complex with miR-32. |
| Pubmed ID | 27871067 |
| Year | 2017 |
| Title | The lncRNA SNHG5/miR-32 axis regulates gastric cancer cell proliferation and migration by targeting KLF4. |
| External Links |
| Links for SNHG5 | GenBank HGNC lncrnadb Noncode |
| Links for gastric cancer | Omim Cosmic |
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