Detail
LncRNA Name | SNHG7 |
Synonyms | SNHG7, NCRNA00061, MGC16037 |
Region | GRCh38_9:136721366-136728184 Sequence |
Ensembl | ENSG00000233016 |
RefSeq | NR_003672 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | bladder cancer |
ICD-0-3 | C61.9 |
Methods | qRT-PCR ect. |
Sample | Bladder cancer cell lines (T24, J82 and SW780) and normal human bladder cell line (SV-HUC-1), Surgical bladder cancer tissues matched near-cancer tissues |
Expression Pattern | up-regulated |
Function Description | lncRNA-SNHG7 was upregulated in bladder cancer cell lines. After the expression of lncRNA-SNHG7 was downregulated, the proliferation of bladder cancer cells was decreased, the apoptosis was increased, and the invasion ability of cells was decreased. The expression of E-cadherin was increased, but the expression of N-cadherin, vimentin and snail were decreased. Increased expression of lncRNASNHG7 in cancer tissues was significantly related to tumor size, metastasis and stage. |
Pubmed ID | 30003751 |
Year | 2018 |
Title | LncRNA-SNHG7 regulates proliferation, apoptosis and invasion of bladder cancer cells assurance guidelines. |
External Links |
Links for SNHG7 | GenBank HGNC lncrnadb Noncode |
Links for bladder cancer | Omim Cosmic |
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