Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SNHG7
   Synonyms SNHG7, NCRNA00061, MGC16037
   Region GRCh38_9:136721366-136728184    Sequence
   Ensembl ENSG00000233016
   RefSeq NR_003672
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C61.9  
   Methods qRT-PCR ect.
   Sample Bladder cancer cell lines (T24, J82 and SW780) and normal human bladder cell line (SV-HUC-1), Surgical bladder cancer tissues matched near-cancer tissues
   Expression Pattern up-regulated
   Function Description

lncRNA-SNHG7 was upregulated in bladder cancer cell lines. After the expression of lncRNA-SNHG7 was downregulated, the proliferation of bladder cancer cells was decreased, the apoptosis was increased, and the invasion ability of cells was decreased. The expression of E-cadherin was increased, but the expression of N-cadherin, vimentin and snail were decreased. Increased expression of lncRNASNHG7 in cancer tissues was significantly related to tumor size, metastasis and stage.

   Pubmed ID 30003751
   Year 2018
   Title LncRNA-SNHG7 regulates proliferation, apoptosis and invasion of bladder cancer cells assurance guidelines.
   External Links
   Links for  SNHG7 GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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