Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SOX2OT
   Synonyms SOX2-OT, NCRNA00043, SOX2OT, DKFZp761J1324
   Region GRCh38_3:180989762-181836880    Sequence
   Ensembl ENSG00000242808
   RefSeq NR_004053
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung squamous cell carcinoma
   ICD-0-3 C34  M8070/3
   Methods qPCR, RNAi, Western blot, RIP etc.
   Sample cell lines (A549, HCC827, SK-MES-1, NCI-H1299 etc.)
   Expression Pattern up-regulated
   Function Description

Sox2ot exprssion in lung cancer is significantly higher and promotes cancer cell proliferation. Sox2ot plays an important role in regulating lung cancer cell proliferation, and may represent a novel prognostic indicator for the disease.

   Pubmed ID 24927902
   Year 2014
   Title A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival.
   External Links
   Links for  SOX2OT GenBank       HGNC       lncrnadb       Noncode
   Links for  lung squamous cell carcinoma Omim       Cosmic

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