Detail
LncRNA Name | SOX2OT |
Synonyms | SOX2-OT, NCRNA00043, SOX2OT, DKFZp761J1324 |
Region | GRCh38_3:180989762-181836880 Sequence |
Ensembl | ENSG00000242808 |
RefSeq | NR_004053 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | lung squamous cell carcinoma |
ICD-0-3 | C34 M8070/3 |
Methods | qPCR, RNAi, Western blot, RIP etc. |
Sample | cell lines (A549, HCC827, SK-MES-1, NCI-H1299 etc.) |
Expression Pattern | up-regulated |
Function Description | Sox2ot exprssion in lung cancer is significantly higher and promotes cancer cell proliferation. Sox2ot plays an important role in regulating lung cancer cell proliferation, and may represent a novel prognostic indicator for the disease. |
Pubmed ID | 24927902 |
Year | 2014 |
Title | A long noncoding RNA Sox2ot regulates lung cancer cell proliferation and is a prognostic indicator of poor survival. |
External Links |
Links for SOX2OT | GenBank HGNC lncrnadb Noncode |
Links for lung squamous cell carcinoma | Omim Cosmic |
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