Detail
LncRNA Name | SOX2OT |
Synonyms | SOX2-OT, NCRNA00043, SOX2OT, DKFZp761J1324 |
Region | GRCh38_3:180989762-181836880 Sequence |
Ensembl | ENSG00000242808 |
RefSeq | NR_004053 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✔ |
TF | ✔ |
Methylation | ✘ |
Cancer Name | lung squamous cell carcinoma |
ICD-0-3 | C34 M8070/3 |
Methods | qPCR etc. |
Sample | LSCC tissues |
Expression Pattern | up-regulated |
Function Description | In conclusion, eight out of the nine tested genes were recurrently over-expressed, but SOX2 and SOX2OT were the most consistently highly over-expressed and thus are the best candidates to be driver genes of 3q26.3 amplifications. |
Pubmed ID | 20126410 |
Year | 2010 |
Title | SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas. |
External Links |
Links for SOX2OT | GenBank HGNC lncrnadb Noncode |
Links for lung squamous cell carcinoma | Omim Cosmic |
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