Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SOX2OT
   Synonyms SOX2-OT, NCRNA00043, SOX2OT, DKFZp761J1324
   Region GRCh38_3:180989762-181836880    Sequence
   Ensembl ENSG00000242808
   RefSeq NR_004053
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR, RNAi etc.
   Sample HCC tissues, cell lines (HepG2, SMMC-7721)
   Expression Pattern up-regulated
   Function Description

lncRNA Sox2ot expression level was significantly higher in HCC tissues compared with adjacent non-tumor tissues. High expression of lncRNA Sox2ot was associated with histological grade, TNM stage, and vein invasion.

   Pubmed ID 26097588
   Year 2015
   Title Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis.
   External Links
   Links for  SOX2OT GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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