Detail
| LncRNA Name | SOX2OT |
| Synonyms | SOX2-OT, NCRNA00043, SOX2OT, DKFZp761J1324 |
| Region | GRCh38_3:180989762-181836880 Sequence |
| Ensembl | ENSG00000242808 |
| RefSeq | NR_004053 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | esophageal squamous cell cancer |
| ICD-0-3 | |
| Methods | qPCR, RNAi etc. |
| Sample | ESCC tissues, cell lines (NT2, U-87 MG etc.) |
| Expression Pattern | up-regulated |
| Function Description | The results of qPCR revealed that SOX2OT-S1 and SOX2OT-S2 were overexpressed in tumor samples of ESCC, compared to their marginal non-tumor tissue counterparts. Furthermore, overexpression of SOX2OT-S2 in tumor samples, similar to SOX2 and OCT4, was statistically significant. |
| Pubmed ID | 24105929 |
| Year | 2014 |
| Title | Two novel splice variants of SOX2OT, SOX2OT-S1, and SOX2OT-S2 are coupregulated with SOX2 and OCT4 in esophageal squamous cell carcinoma. |
| External Links |
| Links for SOX2OT | GenBank HGNC lncrnadb Noncode |
| Links for esophageal squamous cell cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.