Detail
LncRNA Name | BC200 |
Synonyms | BCYRN1, BC200, BC200a, LINC00004, NCRNA00004 |
Region | GRCh38_2:47335315-47335514 Sequence |
Ensembl | ENSG00000236824 |
RefSeq | NR_001568 |
Circulating | ✘ |
Drug-resisitant | ✔ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✔ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR, ChIP etc. |
Sample | cell lines (MCF-7, T47D, MDA-MB-231) |
Expression Pattern | up-regulated |
Function Description | In this study, we show that BC200 is upregulated in breast cancer; among breast tumor specimens there is a higher level of BC200 in estrogen receptor (ER) positive than in ER-negative tumors. Further experiments show that activation of estrogen signaling induces expression of BC200. |
Pubmed ID | 27277684 |
Year | 2016 |
Title | Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis. |
External Links |
Links for BC200 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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