Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name BC200
   Synonyms BCYRN1, BC200, BC200a, LINC00004, NCRNA00004
   Region GRCh38_2:47335315-47335514    Sequence
   Ensembl ENSG00000236824
   RefSeq NR_001568
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR, ChIP etc.
   Sample cell lines (MCF-7, T47D, MDA-MB-231)
   Expression Pattern up-regulated
   Function Description

In this study, we show that BC200 is upregulated in breast cancer; among breast tumor specimens there is a higher level of BC200 in estrogen receptor (ER) positive than in ER-negative tumors. Further experiments show that activation of estrogen signaling induces expression of BC200.

   Pubmed ID 27277684
   Year 2016
   Title Regulation of alternative splicing of Bcl-x by BC200 contributes to breast cancer pathogenesis.
   External Links
   Links for  BC200 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.