Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SPRY4-IT1
   Synonyms SPRY4-IT1, SPRIGHTLY
   Region NA    Sequence
   Ensembl ENSG00000281881
   RefSeq NR_131221
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name melanoma
   ICD-0-3  M8720/3
   Methods qPCR etc.
   Sample blood
   Expression Pattern up-regulated
   Function Description

SPRY4-IT1 expression is high in melanoma patients but low in healthy controls, and is closely associated with tumor site and tumor stage. Elevated SPRY4-IT1 significantly reduces overall survival rates of patients and is considered as an independent prognostic factor in patients with melanoma.

   Pubmed ID 27239436
   Year 2016
   Title Clinical significance of long noncoding RNA SPRY4-IT1 in melanoma patients.
   External Links
   Links for  SPRY4-IT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  melanoma Omim       Cosmic

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