Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SPRY4-IT1
   Synonyms SPRY4-IT1, SPRIGHTLY
   Region NA    Sequence
   Ensembl ENSG00000281881
   RefSeq NR_131221
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung adenocarcinoma
   ICD-0-3 C34  M8140/3
   Methods qPCR
   Sample cell lines (H23, H1299, A549 and SPC-A1)
   Expression Pattern up-regulated
   Function Description

The results showed that SPRY4-IT1 was significantly up-regulated in LUAD tissues. Further analysis indicated that LUAD patients with high SPRY4-IT1 expression have significantly poorer overall survival in Chinese LUAD patients.

   Pubmed ID 28881629
   Year 2017
   Title Up-regulation of long non-coding RNA SPRY4-IT1 promotes tumor cell migration and invasion in lung adenocarcinoma
   External Links
   Links for  SPRY4-IT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  lung adenocarcinoma Omim       Cosmic

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