Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SPRY4-IT1
   Synonyms SPRY4-IT1, SPRIGHTLY
   Region NA    Sequence
   Ensembl ENSG00000281881
   RefSeq NR_131221
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR etc.
   Sample blood, cell lines (Hep-3B, HepG2, HuH-7 etc.)
   Expression Pattern up-regulated
   Function Description

In the present study, we focused on the expression pattern of lncRNA SPRY4 intronic transcript 1 (SPRY4-IT1) and its clinical significance in HCC diagnostics. The levels of SPRY4-IT1 were upregulated in HCC and were associated with tumor differentiation, tumor size and tumor-node-metastasis (TNM) stage.

   Pubmed ID 27278245
   Year 2016
   Title Potential diagnostic value of lncRNA SPRY4-IT1 in hepatocellular carcinoma.
   External Links
   Links for  SPRY4-IT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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