Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name SPRY4-IT1
   Synonyms SPRY4-IT1, SPRIGHTLY
   Region NA    Sequence
   Ensembl ENSG00000281881
   RefSeq NR_131221
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioma
   ICD-0-3  M9380/3
   Methods qPCR etc.
   Sample glioma tissues
   Expression Pattern up-regulated
   Function Description

The expression level of SPRY4-IT1 was significantly higher in glioma in comparison to normal matched tissue. Furthermore, lncRNA SPRY4-IT1 was associated significantly with WHO grade and tumor size. A significant difference was found that glioma patients with high SPRY4-IT1 expression level had distinctly shorter OS than patients with low SPRY4-IT1 expression level.

   Pubmed ID 27460732
   Year 2016
   Title Long noncoding RNA SPRY4-IT1 is a prognostic factor for poor overall survival and has an oncogenic role in glioma.
   External Links
   Links for  SPRY4-IT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioma Omim       Cosmic

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