Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name SRA1
   Synonyms SRA1, SRA, SRAP, STRAA1, pp7684
   Region GRCh38_5:140537340-140558252    Sequence
   Ensembl ENSG00000213523
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods qPCR etc.
   Sample breast cancer tissues
   Expression Pattern differential expression
   Function Description

Subgroup analysis showed that SRA expression was similar in ER+/PR+ (median = 65.5, n = 8) and in ER-/PR- (median = 94.6, n = 5) tumors. Interestingly, SRA expression in these two subgroups was significantly lower than that observed in ER+/PR- (median = 156.4, n = 6) and ER-/PR+ (median = 144.8, n = 8) tumors. A variant form of SRA, presenting a deletion of 203 bp within the SRA core sequence, was also observed in breast tumor tissues. The relative expression of this new SRA isoform correlated with tumor grade.

   Pubmed ID 10485452
   Year 1999
   Title Expression of the steroid receptor RNA activator in human breast tumors.
   External Links
   Links for  SRA1 GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.