Detail
LncRNA Name | SRA1 |
Synonyms | SRA1, SRA, SRAP, STRAA1, pp7684 |
Region | GRCh38_5:140537340-140558252 Sequence |
Ensembl | ENSG00000213523 |
RefSeq | NA |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✔ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR etc. |
Sample | breast cancer tissues |
Expression Pattern | differential expression |
Function Description | Subgroup analysis showed that SRA expression was similar in ER+/PR+ (median = 65.5, n = 8) and in ER-/PR- (median = 94.6, n = 5) tumors. Interestingly, SRA expression in these two subgroups was significantly lower than that observed in ER+/PR- (median = 156.4, n = 6) and ER-/PR+ (median = 144.8, n = 8) tumors. A variant form of SRA, presenting a deletion of 203 bp within the SRA core sequence, was also observed in breast tumor tissues. The relative expression of this new SRA isoform correlated with tumor grade. |
Pubmed ID | 10485452 |
Year | 1999 |
Title | Expression of the steroid receptor RNA activator in human breast tumors. |
External Links |
Links for SRA1 | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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