Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name ST7OT1
   Synonyms ST7-AS1, ST7AS1, ST7OT1
   Region GRCh38_7:116952446-116954334    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioma
   ICD-0-3  M9380/3
   Methods qPCR etc.
   Sample cell lines (U251, U87)
   Expression Pattern up-regulated
   Function Description

MEG3 and ST7OT1 are up-regulated in both cell lines under apoptosis induced using both agents. The induction of GAS5 is only clearly detected during DOX-induced apoptosis, whereas the up-regulation of neat1 and MIR155HG is only found during RES-induced apoptosis in both cell lines. However, TUG1, BC200 and MIR155HG are down regulated when necrosis is induced using a high dose of DOX in both cell lines.

   Pubmed ID 25645334
   Year 2015
   Title Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells
   External Links
   Links for  ST7OT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioma Omim       Cosmic

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