Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TC0101686
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name epithelial ovarian cancer
   ICD-0-3 C56.9  
   Methods microarray, qPCR etc.
   Sample epithelial ovarian cancer tissues, cell lines (SKOV3 etc.)
   Expression Pattern down-regulated
   Function Description

Notably, three candidates (TC0100223, TC0101686 and TC0101441) were aberrantly expressed in ERa-positive compared to ERa-negative EOC tissues, showing correlations with some malignant cancer phenotypes such as advanced FIGO stage and/or high histological grade. Furthermore, multivariate analysis indicated that TC0101441 was an independent prognostic factor for overall survival.

   Pubmed ID 24481591
   Year 2014
   Title Expression and clinical significance of estrogen-regulated long non-coding RNAs in estrogen receptor a-positive ovarian cancer progression.
   External Links
   Links for  TC0101686 GenBank       HGNC       lncrnadb       Noncode
   Links for  epithelial ovarian cancer Omim       Cosmic

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