Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TCONS_00026506
   Synonyms lnc-EPG5-2, NONHSAT059090
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods microarray, qPCR etc.
   Sample cell line (HCT116)
   Expression Pattern up-regulated
   Function Description

To validate the microarray results, we randomly selected 6 differentially expressed lncRNAs (TCONS_00026506, ENST00000468960, NR_038990, ENST00000575202, ENST00000539009 and ENST00000544591) between CRR-HCT116 and parental HCT116 cells to confirm their expression levels by qPCR. Changes in lncRNA expression are involved in 5-FU-based CRR in CRC cells.

   Pubmed ID 25921151
   Year 2015
   Title Microarray Analysis of Long Non-coding RNA Expression Profile Associated with 5-Fluorouracil-Based Chemoradiation Resistance in Colorectal Cancer Cells.
   External Links
   Links for  TCONS_00026506 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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