Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name BCAR4
   Synonyms NA
   Region GRCh38_16:11819829-11828845    Sequence
   Ensembl ENSG00000262117
   RefSeq NR_024049
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR etc.
   Sample NSCLC tissues, cell lines (L78, A549, H1229, H358, and H1650)
   Expression Pattern up-regulated
   Function Description

The expression level of lncRNA BCAR4 was significantly higher in NSCLC tissues compared to their matched non-tumor tissues. Moreover, BCAR4 expression was significantly upregulated in NSCLC cell lines, when compared to the normal human bronchial epithelial cell line BEAS-2B. In addition, the BCAR4 expression was associated with the lymph node metastasis, distant metastasis and clinical stage.

   Pubmed ID 28077810
   Year 2017
   Title Increased Expression of Long Non-Coding RNA BCAR4 Is Predictive of Poor Prognosis in Patients with Non-Small Cell Lung Cancer.
   External Links
   Links for  BCAR4 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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