Detail
| LncRNA Name | TINCR |
| Synonyms | TINCR, LINC00036, NCRNA00036, PLAC2, onco-lncRNA-16 |
| Region | GRCh38_19:5558167-5578349 Sequence |
| Ensembl | ENSG00000223573 |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 M8046/3 |
| Methods | Microarray, qPCR, RNAi, RIP etc. |
| Sample | cell lines (MRC-5, PC9, H1299, H522, A549, 95D,95C and H2172), 293T cell,NSCLC tissues |
| Expression Pattern | up-regulated |
| Function Description | TINCR can interact with BRAF to facilitate its kinase activity, thereby leading to activation of oncogenic mitogen-activated protein kinase (MAPK) pathway. |
| Pubmed ID | 29427662 |
| Year | 2018 |
| Title | TINCR facilitates non-small cell lung cancer progression through BRAF-activated MAPK pathway. |
| External Links |
| Links for TINCR | GenBank HGNC lncrnadb Noncode |
| Links for non small cell lung cancer | Omim Cosmic |
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