Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TNXA
   Synonyms TNXA, D6S103E, HXBL, TNX, XA
   Region GRCh38_6:32008614-32012472    Sequence
   Ensembl ENSG00000248290
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods microarray, qPCR, RNAi etc.
   Sample bladder cancer tissues
   Expression Pattern down-regulated
   Function Description

Four lncRNAs were selected for further confirmation of microarray results using qPCR. These lncRNAs were among the most downregulated or upregulated lncRNAs. Data analysis showed that KRT19P3 was upregulated and TNXA, CTA-134P22.2 and CTC-276P9.1 were downregulated in bladder cancer samples compared with matched normal tissues.these deregulated lncRNAs play a key or partial role in the development and/or progression of bladder cancer.

   Pubmed ID 24944692
   Year 2014
   Title Long noncoding RNA expression signatures of bladder cancer revealed by microarray.
   External Links
   Links for  TNXA GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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