Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TP53TG1
   Synonyms TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1, H_RG012D21.9
   Region GRCh38_7:87325225-87345515    Sequence
   Ensembl ENSG00000182165
   RefSeq NR_015381
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods microarray, MSP-PCR, Immunohistochemistry etc.
   Sample gastric cancer tissues, cell lines (MKN-45, MKN-7, TGBC11TKB, KATO-III, SNU-1 and GCIY)
   Expression Pattern differential expression
   Function Description

We found TP53TG1 hypermethylation in 26% (45 of 173) of the gastric neoplasms studied. Presence of TP53TG1 hypermethylation was significantly associated with shorter progression-free survival.

   Pubmed ID 27821766
   Year 2016
   Title Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer.
   External Links
   Links for  TP53TG1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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