Detail
| LncRNA Name | TP73-AS1 |
| Synonyms | TP73-AS1, KIAA0495, PDAM |
| Region | GRCh38_1:3735601-3747336 Sequence |
| Ensembl | ENSG00000227372 |
| RefSeq | NR_033708 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, Western blot, etc. |
| Sample | ovarian cancer tissues, cell lines (OVCA429, OVCA433, SKOV3, HOSE) |
| Expression Pattern | up-regulated |
| Function Description | upregulation of TP73-AS1 was associated with poor prognosis. overexpression of TP73-AS1 promoted cell proliferation, invasion, and migration of OVCA429 cells. TP73-AS1 overexpression enhanced the expression of MMP2 and MMP9 in ovarian cancer cells. |
| Pubmed ID | 29904939 |
| Year | 2018 |
| Title | The lncRNA TP73-AS1 promotes ovarian cancer cell proliferation and metastasis via modulation of MMP2 and MMP9. |
| External Links |
| Links for TP73-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for ovarian cancer | Omim Cosmic |
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