Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TPT1-AS1
   Synonyms TPT1-AS1
   Region GRCh38_13:45341345-45393413    Sequence
   Ensembl ENSG00000170919
   RefSeq NR_024458
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name glioma
   ICD-0-3  M9380/3
   Methods microarray, qPCR etc.
   Sample glioma tissues
   Expression Pattern down-regulated
   Function Description

The expression of four lncRNAs in different grades showed that AGAP2-AS1, LINC01198 and MIR155HG were increased with tumor grade, while TPT1-AS1 was decreased. Knockdown of AGAP2-AS1 can inhibit the cell proliferation, migration and invasion, while increase the apoptosis cell rates in vitro.

   Pubmed ID 27764782
   Year 2016
   Title LncRNA profile study reveals four-lncRNA signature associated with the prognosis of patients with anaplastic gliomas.
   External Links
   Links for  TPT1-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  glioma Omim       Cosmic

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