Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TRERNA1
   Synonyms TRERNA1, LINC00651, treRNA, ncRNA-a7
   Region GRCh38_20:50040716-50041504    Sequence
   Ensembl ENSG00000231265
   RefSeq NR_051976
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR, RNAi, Western blot, Dual-luciferase reporter assay etc.
   Sample cell lines (HepG2, Huh7)
   Expression Pattern up-regulated
   Function Description

We further examined the expression profile of treRNA and miR-190a in 24 pairs of HCC tissues and adjacent normal tissues. miR-190a exhibited a significantly low expression in HCC tissues compared to adjacent normal tissues. Meanwhile, an elevated expression of treRNA was observed in HCC tissue compared to adjacent normal tissue.

   Pubmed ID 26608035
   Year 2015
   Title miR-190a inhibits epithelial-mesenchymal transition of hepatoma cells via targeting the long non-coding RNA treRNA.
   External Links
   Links for  TRERNA1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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