Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TRPM2-AS
   Synonyms TRPM2-AS, TRPM2-AS1
   Region GRCh38_21:44414588-44425272    Sequence
   Ensembl ENSG00000230061
   RefSeq NR_109964
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name prostate cancer
   ICD-0-3 C61.9  
   Methods microarray, qPCR etc.
   Sample cell line (PC3)
   Expression Pattern differential expression
   Function Description

This essential role, coupled to the TRPM2-AS low-expression levels in healthy tissues, makes this ncRNA a suitable therapeutic target for further clinical studies. To get insights into the survival mechanism controlled by this molecule, we ablated its expression in prostate cancer cells and performed a genome-wide analysis of the transcripts differentially regulated in dying cells.

   Pubmed ID 26484139
   Year 2014
   Title Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell.
   External Links
   Links for  TRPM2-AS GenBank       HGNC       lncrnadb       Noncode
   Links for  prostate cancer Omim       Cosmic

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