Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TUBA4B
   Synonyms TUBA4B, TUBA4
   Region GRCh38_2:219253243-219272188    Sequence
   Ensembl ENSG00000243910
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods qPCR, Cell proliferation assay etc.
   Sample NSCLC tissues, cell lines (SPCA-1, NCI-H1299, A549, NCI-H441, LTEP-a2)
   Expression Pattern down-regulated
   Function Description

We found TUBA4B was lower expressed in NSCLC and five cell lines. The lower expression of TUBA4B was remarkably correlated with advanced TNM stage and lymph node metastasis and served as a predictor for overall survival of NSCLC.

   Pubmed ID 27411923
   Year 2016
   Title Low Expression LncRNA TUBA4B is a Poor Predictor of Prognosis and Regulates Cell Proliferation in Non-Small Cell Lung Cancer.
   External Links
   Links for  TUBA4B GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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