Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TUC338
   Synonyms PCBP2-OT1
   Region GRCh38_12:53464468-53465057    Sequence
   Ensembl ENSG00000282977
   RefSeq NR_109828
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung cancer
   ICD-0-3 C34  
   Methods qPCR, Western blot
   Sample lung cancer tissues, cell lines (A549, H1755, SK-MES-1, H1299)
   Expression Pattern up-regulated
   Function Description

the expression of TUC338 was correlated with the overall survival, tumor size and lymph node metastasis in patients, but not with age and gender.the activity of lung cancer cells was decreased, as well as the invasion ability after interference with TUC338.TUC338 can promote the development of lung cancer through regulating MAPK pathway.

   Pubmed ID 29424901
   Year 2018
   Title LncRNA TUC338 promotes invasion of lung cancer by activating MAPK pathway.
   External Links
   Links for  TUC338 GenBank       HGNC       lncrnadb       Noncode
   Links for  lung cancer Omim       Cosmic

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