Detail
| LncRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618 |
| Region | GRCh38_22:30969245-30979395 Sequence |
| Ensembl | ENSG00000253352 |
| RefSeq | NR_002323 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | cholangiocarcinoma |
| ICD-0-3 | M810/3 |
| Methods | qPCR, Western blot etc. |
| Sample | CCA tissues, cell lines (QBC939, Huh-28, HuCCT1, KMBC, CCLP-1, HCCC-9810 and RBE) |
| Expression Pattern | up-regulated |
| Function Description | up-regulation of TUG1 in both CCA tissues and cell lines. overexpression of TUG1 is linked to tumor size (p=0.005), TNM stage (p=0.013), postoperative recurrence (p=0.036) and overall survival (p=0.010) of CCA patients. TUG1 may be a rational CCA-related prognostic factor and therapeutic target. |
| Pubmed ID | 29029475 |
| Year | 2017 |
| Title | The prognostic potential and carcinogenesis of long non-coding RNA TUG1 in human cholangiocarcinoma. |
| External Links |
| Links for TUG1 | GenBank HGNC lncrnadb Noncode |
| Links for cholangiocarcinoma | Omim Cosmic |
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