Detail
| LncRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618 |
| Region | GRCh38_22:30969245-30979395 Sequence |
| Ensembl | ENSG00000253352 |
| RefSeq | NR_002323 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP |
| Sample | pancreatic tumor tissues, cell lines (PANC-1, AsPC-1, HEK 293T) |
| Expression Pattern | up-regulated |
| Function Description | TUG1 was overexpressed in PC tissues and cell lines, and high expression of TUG1 predicted poor prognosis. at least partially, by functioning as an endogenous â??spongeâ?? and competing for miR-382 binding to the miRNA target EZH2. |
| Pubmed ID | 28813705 |
| Year | 2017 |
| Title | The Lncrna-TUG1/EZH2 Axis Promotes Pancreatic Cancer Cell Proliferation, Migration and EMT Phenotype Formation Through Sponging Mir-382 |
| External Links |
| Links for TUG1 | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic cancer | Omim Cosmic |
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