Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name TUG1
   Synonyms TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618
   Region GRCh38_22:30969245-30979395    Sequence
   Ensembl ENSG00000253352
   RefSeq NR_002323
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name cervical cancer
   ICD-0-3 C53  
   Methods qPCR, Western blot etc.
   Sample cervical cancer tissues, cell lines (HeLa, CaSki)
   Expression Pattern up-regulated
   Function Description

TUG1 expression was upregulated in cervical cancer tissues and correlated with advanced clinical features and poor overall survival.In addition, our results indicated that TUG1 could act as an endogenous sponge by directly binding to miR-138-5p and suppressed miR-138-5p expression.

   Pubmed ID 29029428
   Year 2017
   Title Long non-coding RNA TUG1 promotes cervical cancer progression by regulating the miR-138-5p-SIRT1 axis
   External Links
   Links for  TUG1 GenBank       HGNC       lncrnadb       Noncode
   Links for  cervical cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.