Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TUG1
   Synonyms TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618
   Region GRCh38_22:30969245-30979395    Sequence
   Ensembl ENSG00000253352
   RefSeq NR_002323
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name urothelial cancer
   ICD-0-3  M8120/3
   Methods qPCR
   Sample urothelial carcinoma tissues, cell lines (VM-CUB1, SW-1710, HT-1376, 5637, and BFTC-905)
   Expression Pattern differential expression
   Function Description

Altered expression of individual lncRNAs was associated with overall survival, but not consistently between both patient cohorts. Interestingly, lower expression of TUG1 in a subset of UC patients with muscle-invasive tumours was significantly correlated with worse OS in both cohorts.

   Pubmed ID 28430799
   Year 2017
   Title Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma
   External Links
   Links for  TUG1 GenBank       HGNC       lncrnadb       Noncode
   Links for  urothelial cancer Omim       Cosmic

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