Detail
| LncRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618 |
| Region | GRCh38_22:30969245-30979395 Sequence |
| Ensembl | ENSG00000253352 |
| RefSeq | NR_002323 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | glioblastoma |
| ICD-0-3 | M9440/3 |
| Methods | qPCR, RNAi, Western blot, ChIP, Flow cytometry assay etc. |
| Sample | GBM tissues, cell lines (1228-GSC and 222-GSC) |
| Expression Pattern | up-regulated |
| Function Description | TUG1 expression in GBM tissues (n=24) was significantly higher than in normal brain tissues. Treatment with TUG1-DDS markedly reduced tumour growth compared with control-DDS (CTRL-DDS) together with the downregulation of TUG1 expression |
| Pubmed ID | 27922002 |
| Year | 2016 |
| Title | Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment. |
| External Links |
| Links for TUG1 | GenBank HGNC lncrnadb Noncode |
| Links for glioblastoma | Omim Cosmic |
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